Pharmacists and patients are well aware that metformin may come with a fishy smell when you open the bottle. The smell does not mean the. Some people with Type 2 diabetes say there's something fishy about their medication: its smell. The complaints have to do with metformin. Here, learn about the potential side effects of metformin and its sense of smell; nerve damage; difficulty walking; dementia-like symptoms. Metformin is a true workhorse for diabetics : a study published metformin smell Diabetes Care showed that the number of people who started metformin as their first treatment has increased sincewhile sulfonylureas, another popular diabetes treatment, remained the most popular second-line agent. Lactic acidosis is the harmful buildup of lactic acid in the blood. Any data you provide will be primarily stored and processed in the United States, pursuant to the laws of the United States, which may provide lesser privacy protections than European Economic Area countries. Click at this page what would you do metfotmin an overdose smlel for a friend or family metofrmin Possible side effects of metformin include a runny nose, nausea, and headaches. May and his colleagues wrote to the journal to raise awareness of this issue and questioned whether nausea, one of the most commonly reported side effects of metformin, could in some cases in fact be a reaction the fishy odor.